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All authors contributed to and have approved the final manuscript. Conclusions Long-term outcomes for those dependent on prescription opioids demonstrated clear improvement from baseline. Initial treatment condition i. Institutional Review Board approval was obtained for the follow-up extension from each site. As reported in our month follow-up study Potter et al. Concomitantly, many former heroin users abstained from heroin during the follow-up period. Finally, these findings illustrate the importance of conducting longer-term follow-up studies.

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