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Within the Yorkshire Cancer Network, with a population of 2. Of note, only a small proportion of our patients would have had adequate enough renal function to receive MMC. To date, there has been only one study which has specifically investigated the role of CRT in elderly patients with anal cancer. All 16 patients had biopsy-proven squamous cell carcinoma situated in the anal canal six patients , anal margin six patients or both four patients. With an aging population, the number of cases of anal cancer in elderly frail patients is likely to increase. Three patients did not undergo radiological assessment as they had tumours where the risk of metastatic disease was thought to be low, and in addition there were no symptoms or signs to suggest regional or metastatic spread. Squamous cell carcinoma of the anal canal: treatment by external beam irradiation. A study of 17 patients with anorectal carcinoma. Treatment was well tolerated, with only one patient developing grade 3 RTOG skin toxicity.

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